International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies

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:: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies

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ISSN 2228-9860
eISSN 1906-9642
CODEN: ITJEA8


FEATURE PEER-REVIEWED ARTICLE

Vol.13(11)(2022)

  • Roles and Mechanisms of Action of Eradication Therapy on the Frequency of Chromosomal Aberrations and the Antioxidant System in Children with Gastroduodenal Pathology

    Tatiana Temirbolatovna Boraeva (North Ossetian State Medical Academy, Vladikavkaz, Republic of North Ossetia-Alania, RUSSIA),
    Belita Adnanovna Dzhabrailova (Republican Skin and Venereological Dispensary, Grozny, Republic of Chechnya, RUSSIA),
    Leyla Guzhievna Aliyeva (Moscow State Medical and Dental University named after A. I. Evdokimov, Moscow, RUSSIA),
    Marem Rezvanovna Tsokayeva (Chechen State University named after A.A. Kadyrov, Grozny, Republic of Chechnya, RUSSIA),
    Ulyana Viktorovna Matveeva, Lyudmila Valdemarovna Pavlovskaya (North Ossetian State Medical Academy, Vladikavkaz, Republic of North Ossetia-Alania, RUSSIA),
    Arslan Ayavovich Tatamov (Dagestan State Medical University, Makhachkala, Republic of Dagestan, RUSSIA),
    Kheda Zaiputyevna Erzanukayeva (Republican Clinical Center of Infectious Diseases, Grozny, Republic of Chechnya, RUSSIA),
    Loreta Denilbekovna Makalova, Akhmatova Aza Shamkhanovna (Saratov State Medical University named after V. I. Razumovsky, Saratov, RUSSIA).

    Discipline: Medicine (Gastroenterology).

    ➤ FullText

    doi: 10.14456/ITJEMAST.2022.218

    Keywords:Eradication therapy in children, Peptic ulcer disease of children, gastritis, Helicobacter pylori, Chromosomal aberrations, Antioxidant system

    Abstract
    It is known that various pharmacological drugs induce numerous chromosomal aberrations. The interest of doctors and scientists is focused on the question of the presence and degree of mutagenic effects of drugs used in standardized protocols of eradication therapy in children due to "rejuvenation" and the prevalence of gastroduodenal spectrum pathologies, methods of their elimination and correction, to preserve a healthy karyotype. This work aims to study the mechanisms of development of peptic ulcers, gastritis and other pathologies of the gastroduodenal spectrum associated with Helicobacter pylori, as well as the effect of eradication therapy on the frequency of chromosomal aberrations and the antioxidant system in children.

    Paper ID: 13A11H

    Cite this article:

    Boraeva, T.T., Dzhabrailova, B.A., Aliyeva, L.G., Erzanukayeva, Kh.Z., Makalova, L.D., Matveeva, U.V., Pavlovskaya, L.V., Tatamov, A.A., Maslova, A.Yu., Shamkhanovna, A.A. (2022). Roles and Mechanisms of Action of Eradication Therapy on the Frequency of Chromosomal Aberrations and the Antioxidant System in Children with Gastroduodenal Pathology. International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 13(11), 13A11H, 1-9. http://TUENGR.COM/V13/13A11H.pdf DOI: 10.14456/ITJEMAST.2022.218

References

  1. Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet. 1984 Jun 16;1(8390):1311-5. doi: 10.1016/s0140-6736(84)91816-6
  2. Siddiqui SA, Ali Redha A, Snoeck ER, Singh S, Simal-Gandara J, Ibrahim SA, Jafari SM. Anti-Depressant Properties of Crocin Molecules in Saffron. Molecules. 2022; 27(7):2076. https://doi.org/10.3390/molecules27072076
  3. Maslova AY, Bazaeva KL, Abdullaeva ZA, Khazamova SO, Zeusheva KA, Grechkina TA, Semkina EN, Abramov MA, Mishvelov AE, Povetkin SN. Astrocytes and their Phenomenal Possibilities in the Treatment of Various Neurodegenerative Disorders: An Overview. Journal of Pharmaceutical Research International. 2021;33(33A): 60-68. DOI: 10.9734/jpri/2021/v33i33A31772
  4. Profeta A, Siddiqui SA, Smetana S, Hossaini SM, Heinz V, Kircher C. The impact of Corona pandemic on consumer's food consumption: Vulnerability of households with children and income losses and change in sustainable consumption behavior. J Verbrauch Lebensm. 2021;16(4):305-314. doi: 10.1007/s00003-021-01341-1
  5. Omer, Rabia & Iqbal, Sanaullah & Sajid, Bilal & Hussain, Muhammad & Owaid, Mustafa & Saeed, Farhan & Waheed, Marwa & Shariati, Mohammad Ali & Khan, Muhammad & Ahmad, Toheed. Evaluating the Effect of Prebiotics in the Rehabilitation of Gut Microbiota After Antibiotic Therapy in Rats. Gazi Medical Journal. 2020; 31. 10-14. 10.12996/gmj.2020.03.
  6. Kharkevich DA. Osnovnye napravleniia sozdaniia novykh lekarstvennykh sredstv [New developments in drug discovery]. Eksp Klin Farmakol. 2003 May-Jun;66(3):74-9. Russian.
  7. Boraeva, T. T., Vadaeva, M. A., Matveeva, U. V., Revazova, A. B., Albegova, B. Z., Kanukoeva, D. T., Mishvelov, A. E. and Povetkin, S. N. Dynamics of Diseases of the Upper Digestive Tract in Children, Journal of Pharmaceutical Research International, 2021; 33(38B), 48-57. doi: 10.9734/jpri/2021/v33i38B32098
  8. Maslova AY, Bazaeva KL, Abdullaeva ZA, Khazamova SO, Zeusheva KA, Grechkina TA, Semkina EN, Abramov MA, Mishvelov AE, Povetkin SN. Astrocytes and their Phenomenal Possibilities in the Treatment of Various Neurodegenerative Disorders: An Overview. Journal of Pharmaceutical Research International. 2021;33(33A): 60-68. DOI: 10.9734/jpri/2021/v33i33A31772
  9. Ranjha MMAN, Shafique B, Rehman A, Mehmood A, Ali A, Zahra SM, Roobab U, Singh A, Ibrahim SA and Siddiqui SA (2022) Biocompatible Nanomaterials in Food Science, Technology, and Nutrient Drug Delivery: Recent Developments and Applications. Front. Nutr. 8:778155. doi: 10.3389/fnut.2021.778155
  10. Lopteva MS, Povetkin SN, Pushkin SV, Nagdalian AA. 5% suspension of albendazole echinacea magenta (Echinacea purpurea) Toxicometric Evaluation Entomology and Applied Science Letters. 2018;5(4):30-34.
  11. Khandia, Rekha et al. Codon Usage Analysis of Pro-Apoptotic Bim Gene Isoforms. 2022: 1711-1725
  12. Chshieva FT, Chopikashvili LV, Dzhagaeva SK, Boraeva TT, Filippova JA, Puhaeva EG. Clustogenesis level in children with gastroduodenal diseases. Bull Exp Biol Med. 2010 Oct;149(4):431-3. English, Russian. doi: 10.1007/s10517-010-0963-7.
  13. Zemskov VM, Pronko KN, Ionkin DA, Chzhao AV, Kozlova MN, Barsukov AA, Shishkina NS, Demidova VS, Zemskov AM, Revishvili AS. Immune Status of Pancreatic Cancer Patients Receiving Cryosurgery. Med Sci (Basel). 2019 Jun 22;7(6):73. doi: 10.3390/medsci7060073.
  14. Zemskov AM, Zemskov VM, Zemskov MA, Zoloedov VI, Bolotskikh VI. [Problem of specific and nonspecific factors in the induction and regulation of immunological reactions]. Zh Mikrobiol Epidemiol Immunobiol. 2005 Jul-Aug;(4):105-9. Russian.
  15. Rzhepakovsky I, Anusha Siddiqui S, Avanesyan S, Benlidayi M, Dhingra K, Dolgalev A, Enukashvily N, Fritsch T, Heinz V, Kochergin S, Nagdalian A, Sizonenko M, Timchenko L, Vukovic M, Piskov S, Grimm WD. Anti-arthritic effect of chicken embryo tissue hydrolyzate against adjuvant arthritis in rats (X-ray microtomographic and histopathological analysis). Food Sci Nutr. 2021 Aug 18;9(10):5648-5669. doi: 10.1002/fsn3.2529
  16. Blinov AV, Nagdalian AA, Povetkin SN, Gvozdenko AA, Verevkina MN, Rzhepakovsky IV, Lopteva MS, Maglakelidze DG, Kataeva TS, Blinova AA, Golik AB, Osipchuk GV, Shariati MA. Surface-Oxidized Polymer-Stabilized Silver Nanoparticles as a Covering Component of Suture Materials. Micromachines. 2022; 13(7):1105. https://doi.org/10.3390/mi13071105
  17. Lutsky MA, Zemskov AM, Savinykh VP, Smelyanets MA, Pozhidaeva YA. Osobennost' techeniya patologicheskogo protsessa pri rasseyannom skleroze, podtverzhdennaya dinamikoi biokhimicheskikh markerov okislitel'nogo stressa [The features of multiple sclerosis pathological progression verified by the dynamics of biochemical markers of oxidative stress]. Zh Nevrol Psikhiatr Im S S Korsakova. 2016;116(10 Pt 2):21-26. Russian. doi: 10.17116/jnevro201611610221-26.
  18. Lucero Y, Lagomarcino AJ, Torres JP, Roessler P, Mamani N, George SA, Huerta N, Gonzalez M, O'Ryan G M. Effect of Helicobacter pylori eradication therapy on clinical and laboratory biomarkers associated with gastric damage in healthy school-aged children: A randomized non-blinded trial. Helicobacter. 2021 Dec;26(6):e12853. doi: 10.1111/hel.12853.
  19. Furuta T, Sugimoto M, Yamade M, Uotani T, Sahara S, Ichikawa H, Yamada T, Osawa S, Sugimoto K, Watanabe H, Umemura K. Effect of dosing schemes of amoxicillin on eradication rates of Helicobacter pylori with amoxicillin-based triple therapy. J Clin Pharmacol. 2014 Mar;54(3):258-66. doi: 10.1002/jcph.195.
  20. Albegova DV, Temuridi EG, Mamieva OV, Platonova KP, Tsoraeva LK, Sokolinskaia VA, Bitieva VV. Rezul'taty obsledovaniia dete? v sem'iakh, otiagoshchennykh nefropatiiami [Results of the examination of children from families with hereditary nephropathies]. Pediatriia. 1990;(2):40-3. Russian.
  21. Plotnikov E, Silnikov V, Gapeyev A, Plotnikov V. Investigation of DNA-damage and Chromosomal Aberrations in Blood Cells under the Influence of New Silver-based Antiviral Complex. Adv Pharm Bull. 2016 Mar;6(1):71-4. doi: 10.15171/apb.2016.011.
  22. Pashin IuV, Kozachenko VI, Zatsepilova TA, Soboleva LS. Kompleksnoe ispytanie genetichesko? aktivnosti shestivalentnogo iona khroma in vitro i in vivo [Complex trial of the genetic activity of the hexavalent chromium ion in vitro and in vivo]. Tsitol Genet. 1981 Sep-Oct;15(5):66-9. Russian
  23. Ilyasov KK, Demchenkov EL, Chernyshkov AS, Rodin IA, Pushkin SV, Povetkin SN, et al. Features of the phytopharmacological preparations in the metaphylaxis of urolithiasis. Pharmacophore. 2020;11(5):66-71
  24. Iwai K, Azuma T, Yonenaga T, Watanabe K, Obora A, Deguchi F, Kojima T, Tomofuji T. Association between dental caries and Helicobacter pylori infection in Japanese adults: A cross-sectional study. PLoS One. 2022 Jul 14;17(7):e0271459. doi: 10.1371/journal.pone.0271459.
  25. Ismail MB, Osman M, Bou Raad E, Achkar M, Hamze M. Seroprevalence of Helicobacter pylori among dyspeptic patients in northern Lebanon: a 6-year retrospective study in two tertiary hospitals. Access Microbiol. 2022 Apr 27;4(4):000337. doi: 10.1099/acmi.0.000337
  26. Burford NG, Webster NA, Cruz-Topete D. Hypothalamic-Pituitary-Adrenal Axis Modulation of Glucocorticoids in the Cardiovascular System. International Journal of Molecular Sciences. 2017; 18(10):2150. https://doi.org/10.3390/ijms18102150
  27. Miftahussurur M, Yamaoka Y. Helicobacter pylori virulence genes and host genetic polymorphisms as risk factors for peptic ulcer disease. Expert Rev Gastroenterol Hepatol. 2015;9(12):1535-47. doi: 10.1586/17474124.2015.1095089
  28. Tovlahanova TJH et al. Study of the Effect of the Image Scanning Speed and the Type of Conductive Coating on the Quality of Sem-Micrographs of Oxide Nano Materials for Medical Use. Ann Med Health Sci Res. 2021;11:S3:60-64
  29. Ford AC, Gurusamy KS, Delaney B, Forman D, Moayyedi P. Eradication therapy for peptic ulcer disease in Helicobacter pylori-positive people. Cochrane Database Syst Rev. 2016 Apr 19;4(4):CD003840. doi: 10.1002/14651858.CD003840.pub5
  30. Gasparetto, Marco & Pescarin, Matilde & Guariso, G. (2012). Helicobacter pylori Eradication Therapy: Current Availabilities. ISRN gastroenterology. 2012. 186734. 10.5402/2012/186734.
  31. Rzhepakovsky IV, Areshidze DA, Avanesyan SS, Grimm WD, Filatova NV, Kalinin AV, Kochergin SG, Kozlova MA, Kurchenko VP, Sizonenko MN, Terentiev AA, Timchenko LD, Trigub MM, Nagdalian AA, Piskov SI. Phytochemical Characterization, Antioxidant Activity, and Cytotoxicity of Methanolic Leaf Extract of Chlorophytum Comosum (Green Type) (Thunb.) Jacq. Molecules. 2022; 27(3):762. https://doi.org/10.3390/molecules27030762


Other issues:
Vol.13(10)(2022)
Vol.13(9)(2022)
Vol.13(8)(2022)
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