Evaluation of the Effectiveness and Safety of the Hybrid Scheme of Eradication Therapy of Helicobacter Pylori Infection

Magomedova, Asiyat Shamilevna; Isaeva Zainab, Magomedovna; Magomedova, Zulfiya Shamilyevna; Ausheva, Lyubov Beslanovna; Drozdenko, Vlas Romanovich; Gabachev, Radjap Lomelievich; Aliev, Ali Magomedovich; Magomedova, Patimat Ahkubegovna; Isaeva, Tanzila Pashaevna; Babatkhanov, Adam Saidalvievich

:: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies

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ISSN 2228-9860
eISSN 1906-9642
CODEN: ITJEA8

FEATURE PEER-REVIEWED ARTICLE

Vol.13(11)(2022)

Evaluation of the Effectiveness and Safety of the Hybrid Scheme of Eradication Therapy of Helicobacter Pylori Infection

Asiyat Shamilevna Magomedova, Zainab Magomedovna Isaeva, Zulfiya Shamilyevna Magomedova (Dagestan State Medical University, Makhachkala, Republic of Dagestan, RUSSIA),
Lyubov Beslanovna Ausheva (Moscow State Medical University named after I.M. Sechenov, Moscow, RUSSIA),
Vlas Romanovich Drozdenko (Rostov State Medical University, Rostov-on-Don, RUSSIA),
Radjap Lomelievich Gabachev (Chechen State University named after A.A. Kadyrov, Grozny, Republic of Chechnya, RUSSIA),
Ali Magomedovich Aliev (Rostov State Medical University, Rostov-on-Don, RUSSIA),
Patimat Ahkubegovna Magomedova(Dagestan State Medical University, Makhachkala, Republic of Dagestan, RUSSIA),
Tanzila Pashaevna Isaeva (Chechen State University named after A.A. Kadyrov, Grozny, Republic of Chechnya, RUSSIA),
Adam Saidalvievich Babatkhanov ( Saratov State Medical University named after V. I. Razumovsky, Saratov, RUSSIA).

Discipline: Medicine.
➤ FullText

DOI: 10.14456/ITJEMAST.2022.222

Keywords: Helicobacter pylori, Helicobacteriosis, Eradication therapy, Hybrid therapy, Four-component therapy, Standard triple therapy; H. pylori.

Abstract
The purpose of this work is to conduct a comprehensive comparative study of the efficacy and safety of a hybrid scheme of eradication therapy in patients with confirmed Helicobacter pylori infection. We conducted a randomized comparative study of 180 people with clinically confirmed helicobacteriosis. Upon completion of drug therapy, patients underwent control instrumental diagnostic studies to analyze the effectiveness and safety of the prescribed treatment. The results of our study showed high efficiency and optimal safety of the hybrid scheme of eradication therapy in the treatment of Helicobacter pylori, in comparison with the standard triple scheme and the four-component bismuth-containing scheme. The effectiveness of this method directly depends on the individual characteristics of the patient, the severity of clinical manifestations of helicobacteriosis, the level of resistance to antibacterial therapy. Important for the optimization of eradication therapy is the study of the acid-forming function of the stomach for the selection of a proton pump inhibitor in the optimal dosage and a pronounced antisecretory effect.
Paper ID: 13A11L
Cite this article:

Magomedova, A.Sh., Isaeva, Z.M., Magomedova, Z.Sh., Ausheva, L.B., Drozdenko, V.R., Gabachev, R.L., ... Babatkhanov, A.S. (2022). Evaluation of the Effectiveness and Safety of the Hybrid Scheme of Eradication Therapy of Helicobacter Pylori Infection. International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 13(11), 13A11L, 1-9. http://TUENGR.COM/V13/13A11L.pdf DOI: 10.14456/ITJEMAST.2022.222

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