International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies


:: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies

ISSN 2228-9860
eISSN 1906-9642



  • Diagnosis of Gastroesophageal Reflux Disease in the Practice of an Otorhinolaryngologist: Association Between Chronic Pathology of the Pharynx and Larynx in Disease

    Arbi Ruslanovich Bitaev (Saratov State Medical University named after V.I.Razumovsky, Saratov, RUSSIA),
    Vakhmurad Vakharbievich Chagaev (MEDSI JSC, Moscow, RUSSIA),
    Askhab Anzorovich Khambiev, Magomed Iusupovich Magomedov, Mokhmad Musaevich Temirsultanov, Magomed Nasukhovich Azizov (Rostov State Medical University, Rostov-on-Don, RUSSIA),
    Kheda Magomedovna Kurbanova(North Ossetian State Medical Academy, Vladikavkaz, Republic of North Ossetia-Alania, RUSSIA),
    Arianna Zaurbegovna Gadzhimuradova (Dagestan State Medical University, Makhachkala, Republic of Dagestan, RUSSIA),
    Liana Gagikovna Soloyan (Rostov State Medical University, Rostov-on-Don, RUSSIA),
    Khava Said-Aminovna Tolkhigova (Chechen State University named after A.A. Kadyrov, Grozny, Republic of Chechnya, RUSSIA).

    Discipline: Medicine, Gastroenterology, Otorhinolaryngology.

    ➤ FullText

    DOI: 10.14456/ITJEMAST.2022.224

    Keywords:Gastroesophageal reflux disease, Pharyngolaryngeal reflux, Symptoms of GERD, Symptoms of pharyngolaryngeal reflux

    Gastroesophageal reflux disease (GERD) is a chronic disease with frequent relapses. Advanced forms of the disease lead to a deterioration in the quality of life of the patient, to prolonged medication or surgical treatment. In addition, there is a problem of the unidentification of GERD due to blurred symptoms and complaints of bronchopulmonary and/or cardiological symptoms, symptoms similar to diseases with which it is customary to contact ENT specialists. In this article, the authors collected information from published scientific sources in order to facilitate the diagnosis of GERD against the background of non-specific symptoms for this disease and their differentiation from ENT diseases. The aim of the work was to create a "roadmap" of differentiation of ENT diseases from GERD.

    Paper ID: 13A11N

    Cite this article:

    Bitaev, A.R., Chagaev, V.V., Khambiev, A.A., Magomedov, M.Iu., Temirsultanov, M.M., Azizov, M.N., Kurbanova, Kh.M., Gadzhimuradova, A.Z., Soloyan, L.G., Tolkhigova, Kh.S.-A. (2022). Diagnosis of Gastroesophageal Reflux Disease in the Practice of an Otorhinolaryngologist: Association Between Chronic Pathology of the Pharynx and Larynx in Disease. International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 13(11), 13A11N, 1-8. http://TUENGR.COM/V13/13A11N.pdf DOI: 10.14456/ITJEMAST.2022.224


  1. Chen J, Brady P. Gastroesophageal Reflux Disease: Pathophysiology, Diagnosis, and Treatment. Gastroenterol Nurs. 2019 Jan/Feb;42(1):20-28. DOI: 10.1097/SGA.0000000000000359
  2. Boraeva, T. T., Vadaeva, M. A., Matveeva, U. V., Revazova, A. B., Albegova, B. Z., Kanukoeva, D. T., Mishvelov, A. E. and Povetkin, S. N. Dynamics of Diseases of the Upper Digestive Tract in Children, Journal of Pharmaceutical Research International, 2021; 33(38B), 48-57. DOI: 10.9734/jpri/2021/v33i38B32098
  3. Vakil, N.; Van Zanten, S.V.; Kahrilas, P.; Dent, J.; Jones, R.; Global Consensus Group. The Montreal definition and classification of gastroesophageal reflux disease: A global evidence-based consensus. Am. J. Gastroenterol. 2006, 101, 1900-1920
  4. Raevskaya AI, Belyalova AA, Shevchenko PP, Karpov SM, Mishvelov AE, Simonov AN, Povetkin SN. et al. Cognitive Impairments in A Range of Somatic Diseases Diagnostics, Modern Approach to Therapy . Pharmacophore. 2020; 11(1):136-41
  5. Galabueva AI, Biragova AK, Kotsoyeva GA, Borukayeva ZK, Yesiev RK, Dzgoeva ZG, et al. Optimization of Modern Methods of Treating Chronic Generalized Periodontitis of Mild Severity. Pharmacophore. 2020;11(1):47-51
  6. Ilyasov KK, Demchenkov EL, Chernyshkov AS, Rodin IA, Pushkin SV, Povetkin SN, et al. Features of the phytopharmacological preparations in the metaphylaxis of urolithiasis. Pharmacophore. 2020;11(5):66-71
  7. Sadyrin E, Swain M, Mitrin B, Rzhepakovsky I, Nikolaev A, Irkha V, Yogina D, Lyanguzov N, Maksyukov S, Aizikovich S. Characterization of Enamel and Dentine about a White Spot Lesion: Mechanical Properties, Mineral Density, Microstructure and Molecular Composition. Nanomaterials (Basel). 2020;10(9):1889. DOI: 10.3390/nano10091889
  8. RzhepakovskyI., SiddiquiS.A., AvanesyanS., BenlidayiM., DhingraK., DolgalevA., EnukashvilyN., FritschT., HeinzV., KocherginS., NagdalianA., SizonenkoM., TimchenkoL., VukovicM., PiskovS., GrimmW-D. Anti- arthritic effect of chicken embryo tissue hydrolyzate against adjuvant arthritis in rats (X- ray microtomographic and histopathological analysis). Food Science & Nutrition. 2021;00:1-22.DOI: 10.1002/fsn3.2529
  9. Poddar U. Gastroesophageal reflux disease (GERD) in children. Paediatr Int Child Health. 2019 Feb;39(1):7-12. DOI: 10.1080/20469047.2018.1489649.
  10. Bledzhyants GA, Mishvelov AE, Nuzhnaya KV, Anfinogenova OI, Isakova JA, Melkonyan RS. The Effectiveness of the medical decision-making support system "electronic clinical pharmacologist" in the management of patient's therapeutic profile. Pharmacophore. 2019;10:76-81
  11. Hite GJ, Mishvelov AE, Melchenko EA, Vlasov AA, Anfinogenova OI, Nuzhnaya CV, et al. Holodoctor planning software real-time surgical intervention. Pharmacophore. 2019;10(3):57-60
  12. Dmitry AnatolyevichDomenyuk, Vladimir AlexandrovichZelensky, Igor Vladimirovich Rzhepakovsky, Oksana Ivanovna Anfinogenova, Application of Laboratory and X-Ray Gentral Studies un Early Diagnostics of Metabolic Disturbances of Bone Tissue in Children with Autoimmune Diabetes Mellitus , Entomol Appl Sci Lett. 2018;5(4):1-12
  13. Jurkiewicz D, Wasko-Czopnik D, Pietruszewska W, Tarnowski W, Baranska M, Kowalczyk M, Jaworski P. Gastroesophageal reflux disease - from the point of view of a gastroenterologist, otolaryngologist and surgeon. Otolaryngol Pol. 2021 Apr 30;75(2):42-50. DOI: 10.5604/01.3001.0014.8478.
  14. Kurin M, Shibli F, Kitayama Y, Kim Y, Fass R. Sorting out the Relationship between Gastroesophageal Reflux Disease and Sleep. Curr Gastroenterol Rep. 2021 Aug 2;23(9):15. DOI: 10.1007/s11894-021-00815-4
  15. Axford SE, Sharp N, Ross PE, Pearson JP, Dettmar PW, Panetti M, Koufman JA. Cell biology of laryngeal epithelial defenses in health and disease: preliminary studies. Ann Otol Rhinol Laryngol. 2001 Dec;110(12):1099-108. DOI: 10.1177/000348940111001203
  16. Johnston N, Bulmer D, Gill GA, Panetti M, Ross PE, Pearson JP, Pignatelli M, Axford SE, Dettmar PW, Koufman JA. Cell biology of laryngeal epithelial defenses in health and disease: further studies. Ann Otol Rhinol Laryngol. 2003 Jun;112(6):481-91. DOI: 10.1177/000348940311200601
  17. Ylitalo R, Ramel S. Extraesophageal reflux in patients with contact granuloma: a prospective controlled study. Ann Otol Rhinol Laryngol. 2002 May;111(5 Pt 1):441-6. DOI: 10.1177/000348940211100509
  18. Halstead LA. Gastroesophageal reflux: A critical factor in pediatric subglottic stenosis. Otolaryngol Head Neck Surg. 1999 May;120(5):683-8. DOI: 10.1053/hn.1999.v120.a91766
  19. Qadeer MA, Colabianchi N, Vaezi MF. Is GERD a risk factor for laryngeal cancer? Laryngoscope. 2005 Mar;115(3):486-91. DOI: 10.1097/01.mlg.0000157851.24272.41
  20. Vaezi MF, Qadeer MA, Lopez R, Colabianchi N. Laryngeal cancer and gastroesophageal reflux disease: a case-control study. Am J Med. 2006 Sep;119(9):768-76. DOI: 10.1016/j.amjmed.2006.01.019
  21. Geterud A, Bove M, Ruth M. Hypopharyngeal acid exposure: an independent risk factor for laryngeal cancer? Laryngoscope. 2003 Dec;113(12):2201-5. DOI: 10.1097/00005537-200312000-00030
  22. Shaker R, Bardan E, Gu C, Kern M, Torrico L, Toohill R. Intrapharyngeal distribution of gastric acid refluxate. Laryngoscope. 2003 Jul;113(7):1182-91. DOI: 10.1097/00005537-200307000-00014
  23. Wong IW, Omari TI, Myers JC, Rees G, Nair SB, Jamieson GG, Wormald PJ. Nasopharyngeal pH monitoring in chronic sinusitis patients using a novel four channel probe. Laryngoscope. 2004 Sep;114(9):1582-5. DOI: 10.1097/00005537-200409000-00015
  24. Tovlahanova TJH et al. Study of the Effect of the Image Scanning Speed and the Type of Conductive Coating on the Quality of Sem-Micrographs of Oxide Nano Materials for Medical Use. Ann Med Health Sci Res. 2021;11:S3:60-64
  25. Khandia, Rekha et al. Codon Usage Analysis of Pro-Apoptotic Bim Gene Isoforms. 2022: 1711-1725
  26. Siddiqui SA, Ali Redha A, Snoeck ER, Singh S, Simal-Gandara J, Ibrahim SA, Jafari SM. Anti-Depressant Properties of Crocin Molecules in Saffron. Molecules. 2022; 27(7):2076. DOI: 10.3390/molecules27072076
  27. DelGaudio JM. Direct nasopharyngeal reflux of gastric acid is a contributing factor in refractory chronic rhinosinusitis. Laryngoscope. 2005 Jun;115(6):946-57. DOI: 10.1097/01.MLG.0000163751.00885.63

Other issues:


Call-for-Scientific Papers
Call-for-Research Papers:
ITJEMAST invites you to submit high quality papers for full peer-review and possible publication in areas pertaining engineering, science, management and technology, especially interdisciplinary/cross-disciplinary/multidisciplinary subjects.

To publish your work in the next available issue, your manuscripts together with copyright transfer document signed by all authors can be submitted via email to Editor @ (please see all detail from Instructions for Authors)

Publication and peer-reviewed process:
After the peer-review process, articles will be on-line published in the available next issue. However, the International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies cannot guarantee the exact publication time as the process may take longer time, subject to peer-review approval and adjustment of the submitted articles.