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:: International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies

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ISSN 2228-9860
eISSN 1906-9642
CODEN: ITJEA8


FEATURE PEER-REVIEWED ARTICLE

Vol.13(11)(2022)

  • Pathogenetic Features and Spread of Non-Pigmented (Amelanotic) Melanoma of the Skin

    Tagir Magometovich Nalgiev (Ingush State University, Magas, Republic Of Ingushetia, RUSSIA),
    Fatima Khamzatovna Dagaeva (North Ossetian State Medical Academy, Vladikavkaz, Republic of North Ossetia-Alania, RUSSIA),
    Zarina Olegovna Khubetsova (North Ossetian State University named after Kosta Levanovich Khetagurov, Vladikavkaz, Republic of North Ossetia-Alania, RUSSIA),
    Abdulla Saydalievich Majidov, Busana Mansurovna Dadasheva (Chechen State University named after A.A. Kadyrov, Grozny, Republic of Chechnya, RUSSIA),
    Madina Tamerlanovna Kadieva (Dagestan State Medical University, Makhachkala, Republic of Dagestan, RUSSIA),
    Igor Alexandrovich Kostylev (St. Petersburg State Medical Academy named after I. I. Mechnikov, St. Petersburg, RUSSIA),
    Madina Yusupovna Latyrova (Ingush State University, Magas, Republic of Ingushetia, RUSSIA),
    Abdusaid Abdumutalibovich Kurbanov (Dagestan State Medical University, Makhachkala, Republic of Dagestan, RUSSIA),
    Silviya Grayrovna Arzumanyan (Rostov State Medical University, Rostov-on-Don, RUSSIA).

    Discipline: Medicine, Dermatology.

    ➤ FullText

    doi: 10.14456/ITJEMAST.2022.215

    Keywords:amelanotic melanoma, dermatoscopy, melanoma, pathogenesis, epidemiology, epiluminescent microscopy, melanocytic skin lesion, non-melanocytic skin lesion

    Abstract
    Amelanotic malignant melanoma (non-pigmented melanoma) is a subtype of skin melanoma with little or no pigment on visual examination and is one of the most difficult-to-diagnose clinical conditions. It can mimic benign and malignant variants of both melanocytic and non-melanocytic lesions. Amelanotic melanoma (AM) accounts for 1.8 to 8.1% of all melanomas. The exact incidence is difficult to calculate since the term pigmented melanoma is often used to clinically describe any melanoma that is only partially devoid of pigment. True non-pigmented melanoma is rare, i.e. it does not produce any discernible eumelanin (so-called pure AM), there are also melanomas producing low levels of eumelanin (i.e. hypomelanous melanomas). Such melanomas may seem pigmented. From a clinical point of view, the diagnosis of non-pigmented melanoma is a difficult task for the reason that the clinical and diagnostic signs that are usually associated with melanomas (asymmetry, uneven borders and variegation of color) are rarely present in AM. Thus, in about 50% of cases, the differential diagnosis varies from inflammatory to benign neoplastic formations, which leads to late diagnosis.

    Paper ID: 13A11E

    Cite this article:

    Nalgiev, T.M., Dagaeva, F.Kh., Khubetsova, Z.O., Majidov, A.S., Dadasheva, B.M., Kadieva, Kostylev, I.A., Latyrova, M.Yu., Kurbanov, A.A., Arzumanyan, S.G. (2022). Pathogenetic Features and Spread of Non-Pigmented (Amelanotic) Melanoma of the Skin. International Transaction Journal of Engineering, Management, & Applied Sciences & Technologies, 13(11), 13A11E, 1-9. http://TUENGR.COM/V13/13A11E.pdf DOI: 10.14456/ITJEMAST.2022.215

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Other issues:
Vol.13(10)(2022)
Vol.13(9)(2022)
Vol.13(8)(2022)
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